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The standard protocol calls for dose increases every four weeks at minimum, and rushing this process is one of the most common reasons people experience severe headaches , fatigue , and intense nausea
Therefore, the Food and Drug Administration (FDA) released a guidance requiring all new drugs for glycemic control in T2DM patients to demonstrate cardiovascular safety, a policy that was continued and further emphasized in the 2020 FDA Guidance for Diabetes Drug Development [7, 8]
By suppressing glucagon, GLP-1 further contributes to better glucose control
its also cheaper than Wegovy
277 Social jetlag, a term that refers to the difference between sleep timing that is adjusted for socially necessary schedules (eg, during the work or school week) and natural sleep timing (eg, on the weekend when there are no social pressures), can be a cause of sleep loss and has been linked to negative health outcomes
