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This is going to be a trillion-dollar drug. @hubermanlab says retatrutide is the peptide thats about to change everything. Currently in a Phase III clinical trial in humans, retatrutide caused up to one-third body weight loss in just six months, with some degree of muscle sparing

This suggests that the hair loss is not strictly dose-dependent in a linear way but rather connected to the metabolic changes that all therapeutic doses trigger, including significant weight loss with tirzepatide

In some people, diverticula keep becoming inflamed or infected despite having been treated successfully in the past

Major trials including SUSTAIN-6 and STEP demonstrate that GLP-1 receptor agonists reduce cardiovascular events and mortality in people with diabetes or obesity