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Polycystic ovary syndrome, oral contraceptives and metabolic issues: New perspectives and a unifying hypothesis

PMID 31490017

Practical Application Green tea (EGCG): Catechins show DPP-4 inhibitory activity in vitro Turmeric (curcumin): Demonstrates competitive DPP-4 inhibition Berberine: Reduces DPP-4 expression in laboratory studies Cinnamon extract: Shows modest DPP-4 inhibitory effects Ginger: Contains compounds with DPP-4 inhibitory potential Olive leaf extract: Polyphenols demonstrate DPP-4 modulation Green tea: 3-4 cups daily, brewed at 160-180F for 2-3 minutes Turmeric: 500-1000mg curcumin with black pepper (enhances absorption) Cinnamon: 1-2 teaspoons daily, preferably Ceylon variety Berberine: 500mg 2-3x daily (consult healthcare provider first) Important: Natural DPP-4 inhibition is modest compared to pharmaceuticals

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition

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