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There is no established mechanism by which Wegovy would be expected to directly worsen lupus disease activity or trigger flares, as it does not have known immunomodulatory effects

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Our previous study found that inhibiting LOX activity (Anti-LOX) promoted tunica albuginea remodeling by reducing collagen crosslinking, which finally increased penile length by 10.54% for adult rats, this effect achieved 17.71% when Anti-LOX was combined to a mechanical force from VED (Anti-LOX + VED) 15

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