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approval code 201901/01, date of approval: 2 May 2019)

The major difference is that with MCAS and mast cell activation disorder, a persons mast cells secrete many mediators of inflammation, such as leukotrienes and prostaglandins, not just histamine-although histamine is an important component

Challenges and future perspectives MASLD is a complex, heterogeneous systemic liver disorder driven by metabolic dysregulation, amplified by inflammation, and sustained by immune imbalance

Semaglutide disrupts multiple steps in this chain

Acknowledgments The authors would like to acknowledge the use of generative AI technology, specifically Scholar AI, based on OpenAI's GPT-4 architecture, for revising the grammar of this paper