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Islet transplantation, a less invasive procedure, is indicated in people with excessive glycaemic lability and frequent Level 3 hypoglycaemia despite optimal medical therapy, and allows for inclusion of older people and those with coronary artery disease who would not be eligible for a whole-pancreas transplant [224, 234, 235]
Dysbiosis, or an imbalance in gut microbiota, is associated with metabolic diseases, especially T2DM, and can cause changes in the signaling pathways of intestinal hormone secretion, leading to various health problems [156]
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The absolute bioavailability of the drug after injection was 76.6582.85% in rats
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