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Thus, the brainstemparticularly the NTSis best understood here as an active integrative hub through which gustatory input may be reweighted by interoceptive and visceral state signals during GLP-1RA treatment, rather than as direct evidence of taste-specific dysfunction in humans
In laboratory studies investigating receptor specific incretin signaling, semaglutide provides a useful reference compound for evaluating the mechanistic differences between single receptor agonists and multi receptor incretin pathway modulators
Especially in obesity grade II and higher, treatment should follow an escalation model based on disease severity and responsenot preference or misconception
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As research continues and regulatory approvals progress, it could play an important role in the future of obesity care in India and globally.
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