Shortages and side effects could play a role, along with steep costs and insurance coverage concerns
FIGURE 4 This is complicated because as a polar, charged tripeptide, transport of GSH is significantly inhibited by the blood-brain barrier (BBB), thus limiting effective delivery to brain-resident immune cells such as microglia which are central drivers of neuroinflammatory pathology (Valdovinos-Flores and Gonsebatt, 2012
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Peptides should be stored in a cool, dry, dark place
Speranza B, Campaniello D, Monacis N, Bevilacqua A, Sinigaglia M, Corbo MR