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In B12 deficiency, DNA synthesis in red blood cell precursors (erythroblasts) can be impaired, preventing the normal maturation and division of these cells, resulting in larger-than-normal red blood cells

Forms of administration and relevance to fertility support: Subcutaneous injection is common in research and allows local delivery near pelvic structures or systemic exposure

Individual results vary considerably, but community experience reveals general patterns

Nevertheless, since the risk of cardiovascular and renal events will remain even with the use of GLP-1RA, there is a great deal of clinical interest in its combined use with SGLT2i and finerenone (Table 4)

Patient evaluation Each patient undergoes a comprehensive medical and sexual history assessment prior to treatment initiation