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4.2 GLP-1-based agents The focus of GLP-1RA development has predominantly been on designing GLP-1 derivatives resistant to DPP-4 enzymatic activity and exhibiting slow renal clearance through chemical modification and pharmaceutical formulation
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With the exception of FOSL1, which was undetectable in all of the samples in the ELISA test, the protein level regulation of IL-1, IL8, HSPA1A by the copper compounds were similar with the gene level regulation
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