Chemotherapy-activated EGFR signaling drives the interaction between LOXL3 and TOM20, leading to the hijacking of LOXL3 to mitochondria, where the lysyl oxidase activity of LOXL3 is enhanced through phosphorylation at the S704 site
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A Phase 2 trial was conducted by Diagen (Croatia) for the treatment of ulcerative colitis
Other Ingredients: Capsule (hydroxypropylmethylcellulose, water), microcrystalline cellulose, magnesium stearate (vegetable source) and silicon dioxide
Kidney Int Suppl 114:S12S19