Proper Storage Required Once reconstituted, store the vial in the refrigerator at 36F 46F (2 8C)
No statement in this article should be interpreted as evidence of clinical efficacy, comprehensive human safety, therapeutic suitability, or regulatory approval
Encourage them to eat B12-rich foods (meat, fish, dairy, eggs) when possible
Cycle breaks become mandatory if you have been on protocol for 12+ weeks continuously or if response has dropped significantly despite dose adjustment
Patients should be reviewed 812 weeks after commencing treatment to assess: Symptomatic improvement, particularly resolution of fatigue and neurological symptoms Haematological response (normalisation of haemoglobin and mean cell volume) Reticulocyte count typically rises within one week, indicating bone marrow response Repeat serum B12 testing is generally not useful after starting parenteral therapy, as levels remain elevated for months