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Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. J Clin Endocrinol Metab

Semaglutide's mechanism involves slowing gastric emptying, enhancing glucose-dependent insulin secretion, and reducing appetite through central nervous system pathways

Tirzepatide was superior on all five key secondary endpoints

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