Overall, our work demonstrates a key signaling interplay between DA and NE in - and -cells as a novel regulatory pathway for pancreatic hormone release and offers the promise of new therapeutic approaches to treat the dysfunctional secretion of insulin and glucagon by targeting peripheral catecholamine receptors
Expanding APEX2 substrates for proximity-dependent labeling of nucleic acids and proteins in living cells
When hormone levels are out of balance whether from stress, aging, poor diet, or environmental toxins the ripple effects can be wide-reaching
Ipamorelin excels in this regard, offering a clean, targeted signal that has made it a gold standard in many research applications
Principal Investigator on A Randomized, Double-blind, Multicentre, Parallel-group, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Aticaprant 10 mg as Adjunctive Therapy in Adult Participants with Major Depressive Disorder (MDD) with Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy. Principal Investigator on A Study of Disease Characteristics and Real-life Standard of Care Effectiveness in Patients with Major Depressive Disorder (MDD) With Anhedonia and Inadequate Response to Current Antidepressant Therapy Including an SSRI or SNR. (Janssen)
