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Tumor-growth concern: Because IGF-1 signalling promotes cell proliferation, there is a theoretical concern it could promote growth of existing tumors

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No, Ozempic is licensed in the UK only for type 2 diabetes management

Changes in HbA1c throughout the study were also not associated with reduced MACE.24 Additionally, the multiple pleiotropic effects of SEMA on metabolic, hepatic and renal function may indirectly contribute to cardiovascular protection.25 The HFpEF programme shows significant symptomatic improvement of heart failure symptoms with preserved ejection fraction (HFpEF) in obese patients treated with SEMA 2.4 mg26 (Fig

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