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In addition, thresholds to define B12 deficiency vary between different countries and centers [14], and while the study objective was to compare HTC, B12, and MMA concentrations regardless of any threshold, we compared the proportion of patients with B12 deficiency and marginal deficiency according to the latest published NICE guidelines [29]
Status checked July 30, 2026 Regulatory status can change
Previous work has shown that the abundance of Lactobacillus reuteri (normalized to a control group) decreases during the onset of obesity and remains suppressed even after dieting in mice 99 , which parallels our observations that vehicle-treated diet-switched mice had lower levels of Lactobacillus than the 5A-1MQ-treated mice, the latter of which also demonstrated greater weight loss
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