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Yes- RDs and Pharmacists are essential in managing these side effects, given GI side effects are the primary reason people discontinue in year one
If further weight loss is needed and the medication is well-tolerated, the dose can be increased in 2.5 mg increments (to 7.5 mg, 10 mg, 12.5 mg, and up to the maximum of 15 mg once weekly for Zepbound) generally every 4 weeks
The latter route has a large advantage of adding circulation time to the drug, allowing long-lasting effects of the drugs, potentially reducing the administration frequency and possibly also lowering gastrointestinal complications, as currently only subcutaneous and very few oral routes have been explored
Even in obese individuals without T2DM, it has proven its value, showing reduced energy intake and body weight while improving blood sugar levels
OXT is crucial for aggression, sexual and maternal behavior, neuromodulation, social memory, and bonding
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